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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Vonjo	Pacritinib	2022-02-28	2028-2030	Primary myelofibrosis

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

,

drug interactions

,

leukemia myeloid chronic atypical bcr-abl negative

,

non-small-cell lung carcinoma

,

,

renal insufficiency

,

t-cell lymphoma peripheral

,

t-cell lymphoma cutaneous

,

b-cell lymphoma

,

,

hepatic insufficiency

,

,

myelodysplastic syndromes

,

myeloproliferative disorders

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

myeloid leukemia acute

,

,

,

myeloid leukemia

,

,

lymphoproliferative disorders

,

mantle-cell lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia acute

,

lymphoid leukemia

,

graft vs host disease

,

b-cell chronic lymphocytic leukemia

,

t-cell lymphoma

,

prostatic neoplasms

,

waldenstrom macroglobulinemia

,

hodgkin disease

,

monocytic leukemia acute

,

myelodysplastic-myeloproliferative diseases

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

breast neoplasms

,

hereditary sensory and autonomic neuropathies

,

,

colorectal neoplasms

,

,

,

aplastic anemia

,

refractory anemia with excess of blasts

,

,

adenocarcinoma of lung

,

hematologic neoplasms

,

b-cell lymphoma marginal zone

,

primary myelofibrosis

,

polycythemia vera

,

essential thrombocythemia

,

,

,

bone marrow diseases

,

thrombocytopenia

,

hematologic diseases

,

,

blood platelet disorders

,

hemorrhagic disorders

,

healthy volunteers/patients

,

inflammatory bowel diseases

,

intestinal diseases

,

rheumatoid arthritis

,

,

Aglatimagene besadenovec

prostatic neoplasms

,

ovarian neoplasms

,

non-small-cell lung carcinoma

,

endometrial neoplasms

,

esophageal neoplasms

,

urinary bladder neoplasms

,

uterine cervical neoplasms

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

pervasive child development disorders

,

human influenza

,

pulmonary hypertension

,

marijuana abuse

,

hepatocellular carcinoma

,

positron-emission tomography

,

pharmacokinetics

,

severe acute respiratory syndrome-related coronavirus

,

,

generalized anxiety disorder

,

,

cutaneous malignant melanoma

,

consciousness disorders

,

,

large cell carcinoma

,

coronavirus infections

,

middle east respiratory syndrome coronavirus

,

,

gastrointestinal diseases

,

digestive system diseases

,

,

,

cholangiocarcinoma

,

muscle hypotonia

,

,

herpes genitalis

,

radiation dosimeters

,

pulmonary arterial hypertension

,

,

prostatic neoplasms

,

,

pancreatic neoplasms

,

breast neoplasms

,

compulsive personality disorder

,

,

,

autistic disorder

,

triple negative breast neoplasms

,

autism spectrum disorder

,

,

,

cigarette smoking

,

,

,

,

castration-resistant prostatic neoplasms

,

neoplasm metastasis

,

propionic acidemia

,

solitary pulmonary nodule

,

cerebral infarction

,

,

alzheimer disease

,

squamous cell carcinoma

,

renal cell carcinoma

,

beta-thalassemia

,

,

adenocarcinoma of lung

,

alcohol-related disorders

,

,

movement disorders

,

borderline personality disorder

,

personality disorders

,

,

,

prediabetic state

,

multiple pulmonary nodules

,

,

liver transplantation

,

fragile x syndrome

,

follicular lymphoma

,

persistent infection

,

,

multiple sclerosis

,

substance-related disorders

,

,

,

squamous cell neoplasms

,

non-hodgkin lymphoma

,

merkel cell carcinoma

,

hidradenitis suppurativa

,

,

multiple myeloma

,

,

neurodegenerative diseases

,

small cell lung carcinoma

,

bronchiolo-alveolar adenocarcinoma

,

latent autoimmune diabetes in adults

,

pancreatic ductal carcinoma

,

,

respiratory sounds

,

pleural solitary fibrous tumor

,

self-injurious behavior

,

,

developmental disabilities

,

asperger syndrome

,

craniocerebral trauma

,

ornithine carbamoyltransferase deficiency disease

,

carbamoyl-phosphate synthase i deficiency disease

,

deficiency diseases

,

inborn errors amino acid metabolism

,

vitamin d deficiency

,

metabolic syndrome

,

smoking cessation

,

,

graft rejection

,

ulcerative colitis

,

,

inflammatory bowel diseases

,

,

,

b-cell lymphoma

,

nutrition disorders

,

alcohol withdrawal delirium

,

huntington disease

,

,

small fiber neuropathy

,

inborn urea cycle disorders

,

out-of-hospital cardiac arrest

,

,

,

diffuse intrinsic pontine glioma

,

brain concussion

,

post-concussion syndrome

,

carcinoma in situ

,

cervical intraepithelial neoplasia

,

uterine cervical dysplasia

,

trichotillomania

,

paramyxoviridae infections

,

salivary gland neoplasms

,

adenoid cystic carcinoma

,

,

digeorge syndrome

,

22q11 deletion syndrome

,

frontotemporal dementia

,

,

anorexia nervosa

,

hemoglobinopathies

,

lewy body disease

,

behavioral symptoms

,

helicobacter infections

,

,

,

healthy volunteers/patients

,

,

diabetes mellitus

,

type 1 diabetes mellitus

,

,

treatment-resistant depressive disorder

,

,

ovarian neoplasms

,

,

traumatic brain injuries

,

,

fallopian tube neoplasms

,

ischemic stroke

,

,

attention deficit disorder with hyperactivity

,

colorectal neoplasms

,

malignant mesothelioma

,

,

,

ovarian epithelial carcinoma

,

urologic neoplasms

,

transitional cell carcinoma

,

squamous cell carcinoma of head and neck

,

peripheral nervous system diseases

,

head and neck neoplasms

,

,

,

glucose metabolism disorders

,

metabolic diseases

,

,

autoimmune diseases

,

drug resistant epilepsy

,

status epilepticus

,

,

,

endometrioid carcinoma

,

mucinous cystadenocarcinoma

,

serous cystadenocarcinoma

,

cystadenocarcinoma

,

immune system diseases

,

endocrine system diseases

,

,

coronary artery bypass

,

treatment-resistant schizophrenia

,

,

spinocerebellar degenerations

,

spinocerebellar ataxias

,

machado-joseph disease

,

cerebellar ataxia

,

mucinous adenocarcinoma

,

peritoneal neoplasms

,

clear cell adenocarcinoma

,

acinar cell carcinoma

,

,

,

kidney neoplasms

,

large b-cell lymphoma diffuse

,

neurotoxicity syndromes

,

burkitt lymphoma

,

,

interdigitating dendritic cell sarcoma

,

latent tuberculosis

,

,

rotator cuff injuries

,

inborn genetic diseases

,

,

postoperative complications

,

,

chronic disease

,

,

somatoform disorders

,

myocardial infarction

,

coronary disease

,

coronary artery disease

,

radiation injuries

,

subarachnoid hemorrhage

,

,

,

intracranial vasospasm

,

emergence delirium

,

,

major depressive disorder

,

non-small-cell lung carcinoma

,

depressive disorder

,

,

,

bipolar disorder

,

obsessive-compulsive disorder

,

psychotic disorders

,

parkinson disease

,

cocaine-related disorders

,

cognitive dysfunction

,

brain neoplasms

,

,

,

alcohol drinking

,

mental disorders

,

,

anxiety disorders

,

,

,

communicable diseases

,

nervous system diseases

,

,

,

dry eye syndromes

,

addictive behavior

,

wounds and injuries

,

heart transplantation

,

allergic conjunctivitis

,

,

sleep initiation and maintenance disorders

,

respiratory tract infections

,

,

myocardial ischemia

,

neurologic gait disorders

,

,

,

tourette syndrome

,

,

neurocognitive disorders

,

keratoconjunctivitis

,

substance withdrawal syndrome

,

suicidal ideation

,

,

,

,

,

left ventricular hypertrophy

,

cardiopulmonary bypass

,

aortic valve stenosis

,

dentin sensitivity

,

,

,

,

,

keratoconjunctivitis sicca

,

,

,

,

chronic obstructive pulmonary disease

,

,

migraine disorders

,

post-traumatic stress disorders

,

irritable bowel syndrome

,

systemic lupus erythematosus

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

restless legs syndrome

,

psychomotor agitation

,

,

,

exploratory behavior

,

,

diabetic neuropathies

,

gender dysphoria

,

insulin resistance

,

,

randomized controlled trials as topic

,

problem behavior

,

abdominal neoplasms

,

temporal lobe epilepsy

,

atrial fibrillation

,

,

autoimmune hepatitis

,

autoimmune polyendocrinopathies

,

cytokine release syndrome

,

,

,

,

stiff-person syndrome

,

growth disorders

,

,

neurodevelopmental disorders

,

conduct disorder

,

,

headache disorders

,

,

central nervous system diseases

,

,

migraine without aura

,

primary headache disorders

,

,

cognitive neuroscience

,

,

paraneoplastic syndromes

,

gingival recession

,

,

persian gulf syndrome

,

,

atherosclerosis

,

,

infectious encephalitis

,

reperfusion injury

,

,

amphetamine-related disorders

,

,

,

central nervous system lupus vasculitis

,

traumatic stress disorders

,

pure autonomic failure

,

shy-drager syndrome

,

multiple system atrophy

,

,

food preferences

,

bacterial infections

,

clostridium infections

,

clostridioides difficile

,

gastroesophageal reflux

,

myofascial pain syndromes

,

,

type 2 diabetes mellitus

,

aortic dissection

,

acute aortic syndrome

,

,

,

patient participation

,

,

,

liver neoplasms

,

,

tobacco use disorder

,

,

deep brain stimulation

,

cortical excitability

,

,

learning disabilities

,

specific learning disorder

,

esophageal neoplasms

,

multiple myeloma

,

plasma cell neoplasms

,

myeloid leukemia

,

healthy volunteers/patients

,

ulcerative colitis

,

,

,

rheumatoid arthritis

,

myeloid leukemia acute

,

atopic dermatitis

,

hidradenitis suppurativa

,

,

,

,

pathologic constriction

,

inflammatory bowel diseases

,

intestinal diseases

pharmacokinetics

,

inflammatory breast neoplasms

,

,

renal cell carcinoma

,

communicable diseases

,

pneumococcal infections

,

immune system diseases

,

triple negative breast neoplasms

,

,

,

,

,

,

,

oligodendroglioma

,

small cell lung carcinoma

,

neoplasm metastasis

,

stomach neoplasms

,

esophageal neoplasms

,

hodgkin disease

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

bronchiolitis obliterans syndrome

,

,

plasma cell neoplasms

,

squamous cell carcinoma of head and neck

,

ovarian epithelial carcinoma

,

human influenza

,

fallopian tube neoplasms

,

biliary tract neoplasms

,

prolymphocytic leukemia

,

pancreatic neoplasms

,

,

hepatocellular carcinoma

,

liver neoplasms

,

head and neck neoplasms

,

pancreatic ductal carcinoma

,

induction chemotherapy

,

,

adenocarcinoma of lung

,

gestational diabetes

,

pregnancy in diabetics

,

coronary disease

,

large b-cell lymphoma diffuse

,

brain neoplasms

,

mucopolysaccharidoses

,

mucopolysaccharidosis i

,

follicular lymphoma

,

hematopoietic stem cell transplantation

,

peripheral arterial disease

,

atherosclerosis

,

intermittent claudication

,

peripheral vascular diseases

,

,

,

,

,

meningococcal meningitis

,

haemophilus infections

,

cutaneous malignant melanoma

,

esophageal squamous cell carcinoma

,

urinary bladder neoplasms

,

,

rectal neoplasms

,

congenital abnormalities

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

erythroblastic leukemia acute

,

hypersensitivity

,

peanut hypersensitivity

,

squamous cell carcinoma

,

squamous cell neoplasms

,

prolymphocytic leukemia t-cell

,

allergic rhinitis

,

,

acquired immunodeficiency syndrome

,

sezary syndrome

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

pulmonary alveolar proteinosis

,

,

t-cell lymphoma peripheral

,

laryngeal neoplasms

,

,

alpha 1-antitrypsin deficiency

,

breast neoplasms

,

colorectal neoplasms

,

multiple myeloma

,

non-small-cell lung carcinoma

,

,

myeloid leukemia acute

,

b-cell chronic lymphocytic leukemia

,

,

,

,

myelodysplastic syndromes

,

,

ovarian neoplasms

,

,

,

graft vs host disease

,

meningococcal infections

,

,

healthy volunteers/patients

,

,

hematologic neoplasms

,

,

pneumococcal pneumonia

,

,

haemophilus influenzae type b

,

,

,

myeloid leukemia

,

,

venous thrombosis

,

rheumatoid arthritis

,

,

bcr-abl positive chronic myelogenous leukemia

,

aplastic anemia

,

thrombotic thrombocytopenic purpura

,

,

neuroendocrine tumors

,

carcinoid tumor

,

,

paraneoplastic syndromes

,

islet cell carcinoma

,

islet cell adenoma

,

,

,

somatostatinoma

,

pulmonary embolism

,

,

,

st elevation myocardial infarction

,

glucose intolerance

,

hematologic diseases

,

inborn genetic diseases

,

blood coagulation disorders

,

x-linked genetic diseases

,

hemorrhagic disorders

,

inherited blood coagulation disorders

,

coagulation protein disorders

,

fetal growth retardation

,

thromboembolism

,

noonan syndrome

,

bacterial meningitis

,

,

myeloproliferative disorders

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

,

type 2 diabetes mellitus

,

type 1 diabetes mellitus

,

glycogen storage disease type ii

,

,

diabetes mellitus

,

prostatic neoplasms

,

non-hodgkin lymphoma

,

multiple sclerosis

,

,

glycogen storage disease type iii

,

relapsing-remitting multiple sclerosis

,

,

,

graft rejection

,

chronic kidney failure

,

insulin resistance

,

renal insufficiency

,

kidney transplantation

,

autologous transplantation

,

acute coronary syndrome

,

myocardial infarction

,

,

,

liver transplantation

,

psychology rejection

,

atrial fibrillation

,

,

,

,

,

,

,

,

,

inferior wall myocardial infarction

,

kidney diseases

,

coronary artery disease

,

immunosuppression therapy

,

,

,

glycogen storage disease

,

,

lymphoproliferative disorders

,

paraproteinemias

,

heart transplantation

,

reperfusion injury

prostatic neoplasms

,

chronic kidney failure

,

renal insufficiency

,

hyperparathyroidism

,

secondary hyperparathyroidism

,

kidney diseases

,

,

carotid intima-media thickness

,

cardiovascular diseases

,

vascular calcification

,

,

,

,

,

haemophilus infections

,

colorectal neoplasms

,

,

rectal neoplasms

,

squamous cell carcinoma of head and neck

,

chronic obstructive pulmonary disease

,

,

multiple myeloma

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

breast neoplasms

,

,

non-small-cell lung carcinoma

,

vision disorders

,

bcr-abl positive chronic myelogenous leukemia

,

,

neoplasm metastasis

,

,

,

,

myeloid leukemia

,

spondylarthritis

,

,

,

,

psoriatic arthritis

,

ankylosing spondylitis

,

retinal vein occlusion

,

,

chronic urticaria

,

,

cystic fibrosis

,

choroidal neovascularization

,

osteitis deformans

,

renal cell carcinoma

,

philadelphia chromosome

,

ovarian neoplasms

,

pituitary acth hypersecretion

,

,

,

myelodysplastic syndromes

,

thrombocytopenia

,

,

diabetic retinopathy

,

retinal neovascularization

,

macular degeneration

,

,

hematologic diseases

,

sickle cell anemia

,

sickle cell trait

,

vaso-occlusive crises

,

,

,

,

,

neuroendocrine tumors

,

,

,

gastrointestinal stromal tumors

,

triple negative breast neoplasms

,

myeloid leukemia acute

,

acth-secreting pituitary adenoma

,

,

pseudomonas aeruginosa

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

respiratory aspiration

,

prostatic neoplasms

,

myelomonocytic leukemia chronic

,

,

wet macular degeneration

,

pathologic neovascularization

,

adenocarcinoma of lung

,

brain neoplasms

,

,

hepatocellular carcinoma

,

stomach neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

carcinoid tumor

,

malignant carcinoid syndrome

,

serotonin syndrome

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

homozygous familial hypercholesterolemia

,

,

lupus nephritis

,

,

axial spondyloarthritis

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

allergic rhinitis seasonal

,

graft vs host disease

,

primary myelofibrosis

,

,

inclusion body myositis

,

juvenile arthritis

,

hereditary autoinflammatory diseases

,

,

familial mediterranean fever

,

diabetes mellitus

,

rheumatoid arthritis

,

hereditary sensory and autonomic neuropathies

,

,

hyperlipoproteinemia type i

,

hyperpituitarism

,

degenerative myopia

,

,

non-hodgkin lymphoma

,

,

pulmonary infarction

,

hodgkin disease

,

behcet syndrome

,

,

,

,

giant cell arteritis

,

,

thyroid neoplasms

,

food hypersensitivity

,

peanut hypersensitivity

,

polymyalgia rheumatica

,

male breast neoplasms

,

,

follicular lymphoma

,

polycythemia vera

,

,

,

myeloid leukemia chronic-phase

,

,

iga glomerulonephritis

,

,

left ventricular hypertrophy

,

pathologic dilatation

,

,

essential hypertension

,

systolic murmurs

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

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